William Li

Former Undergraduate Mentee

Undergraduate mentee (UROP) at MIT who applied polygenic score prediction to investigate Alzheimer's disease heterogeneity. Now MD-PhD student at Harvard.

Polygenic score prediction Alzheimer's disease Disease heterogeneity

Bill was an undergraduate mentee (UROP) at MIT who applied polygenic score prediction to investigate Alzheimer’s disease heterogeneity. Now MD-PhD student at Harvard.

Posts and Publications

Polygenic Scores Sparse Models Epigenomics +1 more

PRISM: ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores

In this study, led by Xiaohe (Lucy) Tian, we showed that ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores (PGS).

Lucy Tian

• Nov 13, 2025 • 1 min read

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William Li

Posts and Publications

PRISM: ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores